

Dr Kieron Lim
Consultant Gastroenterologist & Hepatologist
MBBS, University of London, Member, Royal College of Physicians (UK), Fellow, Academy of Medicine (Gastroenterology) Singapore, Fellow, Royal College of Physicians (Edinburgh)
Liver cancer is one of the leading causes of cancer-related deaths worldwide, partly because it is often diagnosed only after the disease has progressed. In its early stages, liver cancer may cause few or no noticeable symptoms, allowing tumours to grow undetected until treatment options become more limited.
The good news is that advances in screening and diagnostic technologies have made it possible to identify liver cancer earlier, especially among individuals with known risk factors. Early detection not only improves the chances of successful liver cancer treatment but may also provide access to a wider range of treatment options and better long-term outcomes.
Liver cancer remains one of the more common cancers in Singapore, particularly among individuals with chronic liver disease and hepatitis B infection. Understanding who is at risk, when to seek medical attention, and the role of regular screening can make a meaningful difference in the management of liver cancer.
Unlike some cancers that produce noticeable warning signs early on, liver cancer can develop silently. Symptoms such as unexplained weight loss, abdominal pain, fatigue, loss of appetite, or jaundice often appear only when the disease has reached a more advanced stage.
This challenge is compounded by the fact that many liver conditions associated with liver cancer—including chronic hepatitis B, hepatitis C, cirrhosis and non-alcoholic fatty liver disease—can also remain asymptomatic for years. As a result, individuals may not realise they are at increased risk until liver cancer is discovered during investigations for unrelated health concerns.
Because of this, relying solely on symptoms is rarely sufficient. Regular screening and proactive monitoring play a critical role in identifying liver cancer before symptoms develop.
Early diagnosis can significantly influence the success of liver cancer treatment. When liver cancer is detected at an earlier stage, tumours are often smaller and more localised, making them easier to treat effectively.
Some of the key benefits of early detection include:
In contrast, advanced liver cancer may require more complex treatment approaches aimed at controlling disease progression rather than achieving a cure. This is why timely diagnosis remains one of the most important factors influencing treatment success.
While anyone can develop liver cancer, certain individuals face a significantly higher risk and may benefit from regular screening.
These include people with:
For individuals in these higher-risk groups, healthcare providers may recommend periodic liver ultrasound examinations and blood tests to monitor liver health and detect abnormalities early.
Regular screening is particularly important because it allows doctors to identify potential concerns before symptoms appear, increasing the likelihood of successful intervention.
If liver cancer is suspected, a combination of tests will be conducted to assess your liver health and determine whether cancer is present. The exact investigations recommended may vary depending on your symptoms, medical history, and risk factors.
The diagnostic process often begins with a discussion about your medical history, symptoms, and overall health. Your doctor may ask about risk factors such as chronic hepatitis B or C, liver cirrhosis, fatty liver disease, alcohol consumption, and any family history of liver cancer.
Blood tests can provide valuable information about how well your liver is functioning. They may also measure substances such as alpha-fetoprotein (AFP), a tumour marker that can be elevated in some people with liver cancer. While blood tests alone cannot confirm a diagnosis, they can help guide further investigations.
Imaging tests play a key role in detecting abnormalities in the liver. Depending on your situation, your doctor may recommend:
These scans help doctors determine whether a growth is likely to be cancerous and whether additional testing is required.
In some cases, further investigations may be necessary to confirm a diagnosis. This may include a liver biopsy, where a small sample of tissue is collected and examined under a microscope. Your doctor will recommend additional tests only when they are needed to clarify the diagnosis or guide treatment decisions.
Once liver cancer is diagnosed, doctors will assess the stage of the disease and the overall condition of the liver before recommending treatment. Early diagnosis is particularly important, as it may provide access to more treatment options and allow care to begin before the cancer progresses.
Detecting a potential abnormality is only the beginning. Once liver cancer is suspected, timely specialist assessment plays an important role in confirming the diagnosis, determining the stage of the disease, and identifying the most appropriate treatment approach.
Because liver cancer often develops alongside chronic liver conditions, treatment decisions must consider both the cancer and the overall health of the liver. This is where the expertise of a liver cancer specialist becomes invaluable.
A liver cancer doctor can help:
Beyond diagnosis and treatment, a specialist can also help patients navigate complex decisions with greater confidence. Understanding the benefits, risks, and goals of different treatment options allows patients to make informed choices that align with their health needs and priorities.

As liver cancer often develops without noticeable symptoms, early detection remains one of the most effective ways to improve treatment outcomes and expand the range of available treatment options. Regular screening, especially for individuals with known risk factors, can help identify liver cancer at an earlier stage when intervention is most effective.
At Kieron Lim Gastroenterology, our team is committed to supporting patients at every stage of their liver care journey—from risk assessment and screening to diagnosis and comprehensive liver cancer treatment options. Together with our experienced gastroenterologist and hepatologist, Dr Kieron Lim, patients benefit from a proactive approach to liver care that prioritises early detection, personalised treatment planning, and timely intervention when it matters most.
If you have concerns about your liver health or may be at increased risk of liver cancer, schedule a consultation with Dr Lim today to discuss your risk factors, screening options, and the next steps towards protecting your long-term liver health.

Meet Our Doctor
Dr Kieron Lim
MBBS, University of LondonMember, Royal College of Physicians (UK)Fellow, Academy of Medicine (Gastroenterology) SingaporeFellow, Royal College of Physicians (Edinburgh)
Dr Kieron Lim is a senior consultant specialising in Gastroenterology and Hepatology, providing comprehensive care for patients with gastrointestinal conditions in Singapore. His expertise extends to disorders affecting the oesophagus, stomach, colon, liver, pancreas, and gallbladder. Through his experience, Dr Lim enhances patient outcomes by facilitating early detection and timely medical interventions.